Pathogenesis of primary dysmenorrheasex medicine
( one ) the mechanical factors
Uterine cervical canal stenosis or uterine position extreme flexion, causing blood flow not free, the palace cavity accumulates blood, tension increased, uterine spasm contraction, stimulate the nerve receptors, causing bloating and abdominal pain formation of dysmenorrhea, menstrual blood outflow once patency, pain disappears.
( two) nervous and mental factors
Primary dysmenorrhea is also affected by mental, neural factors, mental tension, fear, depression is easy happen dysmenorrhea. Internal or external stress can make lower pain threshold, anxiety, fear and biochemical metabolism of substances, can be through the central nervous system stimulation of the pelvic pain fibers. According to the statistics of dysmenorrhea effect of mother Shi Ke daughter, the daughter of dysmenorrhea occurring rate than the control group ( mother of painless History ) is high; proportion of adolescent girls may be nervous too sensitive or decreased pain threshold.lang yi hao
( three) endocrine factors
Primary dysmenorrhea and menstrual period endometrial prostaglandin release ( prostaglandin, PG ), has been confirmed by the endometrium of patients with dysmenorrhea and menstrual blood prostaglandin F2 alpha ( PGF2 and PGE2 ) content was lower than that of normal women was significantly elevated, and endometrium of PG concentration is higher, dysmenorrhea is more serious also, secretory phase endometrium in PG proliferative phase endometrium concentration is high, in the ovulatory cycle of blood PG content in anovulatory cycle is 5 times; therefore the pain occurs frequently in the ovulation in the menstrual cycle, especially when the endometrium is pipe type whole peeled off before, abdominal pain more intense; tube after discharge, pain disappears. Anovulation endometrium by nature officer progesterone stimulation, which contains PG concentration is very low, generally do not occur dysmenorrhea. Prostaglandin induced contraction of uterine smooth muscle, produce delivery like abdominal cramps of colic. Uterine smooth muscle lasted slightly longer, can make the uterine pressure to 8kPa above, causing uterine blood supply deficiency, when the pressure exceeds the mean arterial pressure can cause uterine ischemia, leading to anaerobic metabolites accumulation, stimulation of pain neurons and dysmenorrhea.Spanische Fliege
